What is Piroxicam?
Nonsteroidal anti-inflammatory drug (NSAID) Piroxicam is also known as Feldene(r). It is used primarily for bladder transitional cell carcinoma. You can also use it to treat degenerative joint diseases, although safer NSAIDs exist.
It has been used in rabbits to treat fractures that result from limb swelling.
It is used in small mammals, dogs, and cats to treat cancer. A lot of drugs can be prescribed for off-label usage in veterinary medicine. These situations may require you to follow the instructions and cautions of your veterinarian as they might have different directions than those listed on the label.
What is the best way to give piroxicam?
Piroxicam can be taken by mouth as a capsule. It should be taken with food, to lessen stomach upset. The medication should take effect in approximately 1 to 2 hours. There should be an improvement in clinical signs.
What happens if I forget to give my pet the medication?
You can skip a dose if you forget. However, if you are close to the time for your next dose, skip it and give it the next time. Then, you can return to your regular dosing schedule. Do not give more than one dose to your pet.
Are there any possible negative side effects?
Piroxicam could cause severe bleeding and ulceration in the gastrointestinal tract and the kidneys being damaged. Other possible adverse effects include central nervous system symptoms like dizziness, ringing of the ears, itching, and rashes, as well as swelling in the limbs. Your veterinarian might notice an increase in liver enzymes during bloodwork.
For cats digestive issues and a reduction in the number of red blood cells, as well as kidney injury are possibilities.
This medication with moderate effects will cease to work in just a few days, however, the effects may be more prolonged in animals suffering from kidney or liver diseases.
Does this medication pose any dangers associated with this medicine?
Piroxicam is not to be used on patients who are sensitive to it or any other non-steroidal antidotes. It should be administered with extreme caution for pets with a recent or past background of ulcers in the gastrointestinal tract or bleeding conditions. It should be used with caution when it comes to pets that have impaired heart function as well as those who are nursing or pregnant.
When pets are older using piroxicam, it is recommended to do so with caution since advancing the age of an animal is associated with a greater risk of adverse reactions.
Piroxicam application in felines is not yet evaluated and must be handled with extreme caution or never at all since cats are more susceptible to kidney damage due to NSAIDs.
Do you know of any interactions with drugs that I must be conscious of?
The following drugs are to be taken with care when piroxicam is used aminoglycosides, anticoagulants bisphosphonates, aspirin, cisplatin corticosteroids, cyclosporine diuretics, digoxin, bound to proteins (such as anti-inflammatory drugs and sulfonamides as well as anticoagulants) methotrexate and SNRIs, SSRIs as well as tacrolimus and tricyclic antidepressants.
Make sure to inform your vet about all medication (including supplements, vitamins, or herbal treatments) your pet is taking.
Do you have any type of monitoring that should be conducted for this drug?
Your pet must be closely monitored for any symptoms of digestive problems like diarrhea, vomiting bloody vomit or stools as well as a decreased appetite. Your veterinarian might monitor your pet to make sure the medication is effective. When using this medication over a long period tests of blood to check kidney function and liver enzymes are recommended every so often.
How can I store piroxicam?
Piroxicam must be kept at room temperatures (below 30 degrees Celsius or 86 degF) in a tightly sealed container, and shielded by light.
What do I do in the event of emergencies?
When you are concerned that you have taken an overdose or an allergic reaction due to medication contact your veterinarian right away. If they are not in the office to assist you, follow their advice for contacting an emergency center.
Special Precautions for Using Piroxicam
Piroxicam is intended to be given to the pet that it has been prescribed for. The medication must be kept out of the reach of pets and children.
Piroxicam is a strain to the digestive tract, which is why it is recommended to use it with caution in animals with known GI or renal issues. It is also recommended to use it with caution in animals that have reduced cardiac function.
Other Uses for Piroxicam in Veterinary Medicine
Piroxicam is also employed for veterinary use as a part of a treatment for cancer, particularly for bladder cancers. Due to its ability to decrease COX-2 enzymes, piroxicam is employed to treat a variety of kinds of tumors, such as nasal epithelial cancers, mammary tumors colorectal tumors, oral-squamous cell cancer, oral melanoma Prostatic cancer, and transitional cells cancer (TCC) that affects the bladder and urinary tract, and osteosarcoma. This is due to the fact that COX-2 enzymes are often increased in these tumors.
Piroxicam is not recommended for patients who are sensitive to it or other NSAIDs. It is recommended to use it with extreme caution when pets have a recent or previous history of ulcers in the gastrointestinal tract or bleeding conditions. It should be administered cautiously in pets suffering from impaired heart function or when nursing or pregnant pets.
Can piroxicam cause constipation in dogs?
Possible Side Effects:
Your pet could be showing signs of depression. For increase in jaundice, drinking, seizures, dizziness, behavioral changes Lethargy, swelling constipation, itching, or shedding or hot spots. Contact your vet. In certain instances, Piroxicam can cause stomach ulceration.